Magnesium: The Controllable Hydro-Reactive Design

Revolutionizing Biomedical Applications with Innovative Magnesium Alloy

By leveraging the metabolizable and non-toxic properties of magnesium, zinc, and calcium, the Controllable Hydro-Reactive Magnesium Alloy alters the entropy values of the alloy, allowing for precise control of its degradation rate based on its application. This technology has been applied to develop the first single-use magnesium alloy hemostatic clip that can be broken down and absorbed into the human body.

What sets the Controllable Hydro-Reactive Magnesium Alloy apart is its ability to break through the limitations of existing technologies. By modifying the mixing entropy value of the alloy, it improves the poor corrosion resistance of traditional magnesium alloys. It can replace traditional magnesium alloys with elements like aluminum, tin, and rare earths, which can be harmful to human health. This design achieves the purpose of alloy design by strengthening the corrosion resistance and mechanical properties of the alloy itself, as well as achieving uniform and controlled degradation.

The realization of the Controllable Hydro-Reactive Magnesium Alloy is a significant achievement. It is the world's first innovative material that allows for the precise control of the degradation rate of the Mg-Zn-Ca alloy. This control ensures a uniform and slow degradation until the alloy is completely absorbed by the human body and can be discharged with body fluids. As a result, there is no need for a second surgery to remove it, eliminating the psychological and physical pain for patients.

The Controllable Hydro-Reactive Magnesium Alloy offers unique properties that make it ideal for biomedical applications. It is safe, biocompatible, and biodegradable, stimulating bone cell activity and resisting the corrosive effects of body fluids. Unlike other materials, no additional surface treatment is required to slow down the degradation rate, reducing manufacturing costs by more than 20%.

The development of the Controllable Hydro-Reactive Magnesium Alloy was not without its challenges. By carefully selecting biocompatible magnesium-zinc-calcium elements, the entropy value of the alloy was modified to provide the most suitable amount of hydrogen production and precise control over the rate of hydrogen production. This innovation seamlessly integrates with current production processes, making it a viable and practical solution.

The Controllable Hydro-Reactive Magnesium Alloy has already gained recognition in the market and has been adopted by medical equipment manufacturers and medical institutions. Its introduction not only accelerates the development of the biomaterial industry but also provides new choices in treatment. The Degradable Magnesium Alloy Blood Vessel Clamp, for example, is a biodegradable medical material that eliminates the need for a second surgery to remove it. It has passed rigorous biological toxicity, irritation, and allergy tests, in accordance with ISO10993 specifications.

The Controllable Hydro-Reactive Magnesium Alloy project started in January 2019 and was completed in November 2020 in Taiwan. Its success has been acknowledged with several international awards, including the Red Dot Design Award in Germany, the Golden Pin Design Award in Taiwan, and The R&D 100 Awards in the USA.

The Controllable Hydro-Reactive Magnesium Alloy, with its groundbreaking design and potential for improving biomedical applications, is a testament to the power of innovation and creative problem-solving. It offers a promising solution for the development of safer and more effective medical implants and devices.